Reads alignments of the SAM/BAM file, returning the alignments as an eduction.

Reads alignment blocks of the SAM/BAM file, returning the blocks as an eduction.

Returns header of the SAM/BAM file.

Returns references of the SAM/BAM file.

Writes alignments to the SAM/BAM file.

Writes alignment blocks of the SAM/BAM file.

Writes header to the SAM/BAM file.

Writes references to the SAM/BAM file.

Returns true if the reader can be randomly accessed, false if not.

Sequentially reads contents of the file.

Returns the file's URL.

Reads contents of the file in given region.

Reads all sequences of FASTA/2BIT file.

Reads metadata of indexed sequences in FASTA/2BIT file.

Reads summaries of sequences in the file.

Reads sequence in region of FASTA/2BIT file.

Writes all sequences to FASTA/2BIT file.

Returns header of VCF/BCF file as a sequence of strings.

Returns meta-info section of VCF/BCF file as a map.

Reads file-offsets of VCF/BCF file

Reads variants of the VCF/BCF file, returning them as a lazy sequence.

Reads randomly variants of the VCF/BCF file, returning them as a lazy sequence.

Writes variants to thee VCF/BCF file.

Returns the source's URL.